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| Toxin Name |
U1-theraphotoxin-Cg1a |
| Source Species |
Chilobrachys guangxiensis |
| Toxin Group |
Theraphotoxin |
| Description |
Toxin with unknown molecular target and function. |
| Discovered |
2005 |
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Sex: female, Prosoma length: 29mm
Photo courtesy of Bastian Rast
Use of photo governed by creative
commons noncommercial license
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| This toxin last updated on Jan 25, 2013 |
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| Current Taxonomy |
| Kingdom |
Animalia |
| Phylum |
Arthropoda |
| Class |
Arachnida |
| Order |
Araneae |
| Infra-order |
Mygalomorphae |
| Family |
Theraphosidae |
| Genus |
Chilobrachys |
| Species |
guangxiensis |
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| Molecular Target |
ED50 |
IC50 |
Kd |
Pharmacophore |
Comment |
| Molecular target unknown |
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| Original Deposition References |
Liao Z., Liang S.P.
Submitted (AUG-2005) to the PDB data bank.
Solution structure of jingzhaotoxin-VII.
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| Other References |
Chen J, Deng M, He Q, Meng E, Jiang L, Liao Z, Rong M, Liang S.
Cell Mol Life Sci 65(15):2431-44 (2008)
Molecular diversity and evolution of cystine knot toxins of the tarantulaChilobrachys jingzhao.
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| Disulfide Bonds |
Posttranslational modifications |
| Left Residue |
Right Residue |
Evidence |
| 2 |
17 |
Experimentally determined |
| 9 |
22 |
Experimentally determined |
| 16 |
29 |
Experimentally determined |
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| Residue Number |
Type |
Symbol |
| 34 |
C-terminal amidation |
NHâ‚‚ |
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| Peptide Sequences |
>as:U1-theraphotoxin-Cg1a_1|sp:B1P1A3 Toxin from venom of the spider Chilobrachys guangxiensis with unknown molecular target and function
MKTSALFVIFGLVLLFCNSFAAELKTTGRGCGGLMAGCDGKSTFCCSGYNCSPTWKWCVY
ARPGRR |
Full BLAST |
BLAST mature toxin only
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>as:U1-theraphotoxin-Cg1a_2|sp:P0C2X7 Partial sequence of a toxin from venom of the spider Chilobrachys guangxiensis with unknown molecular target and function
GCGGLMAGCDGKSTFCCSGYNCSPTWKWCVYARP |
Full BLAST
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>as:U1-theraphotoxin-Cg1a_3|sp:B1P1A4 Toxin from venom of the spider Chilobrachys guangxiensis with unknown molecular target and function
MKTSALFVIFGLVLLFCNSFAAELEMTGRGCGGLMAGCDGKSTFCCSGYNCSPTWKWCVY
ARPGRR |
Full BLAST |
BLAST mature toxin only
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| mRNA Sequences |
>as:U1-theraphotoxin-Cg1a_1|gb:EU233834 cDNA sequence of a toxin from the venom gland of the spider Chilobrachys guangxiensis
ACAGCGACTACACTTAGTATCCCCTGAAGATTCTAGCTATCCGTACGGCGAGTAATCATG
AAGACGTCCGCTTTATTCGTCATTTTTGGATTAGTCCTGCTTTTCTGCAATTCATTTGCA
GCTGAACTGAAAACGACCGGAAGAGGTTGTGGAGGACTTATGGCTGGATGTGATGGAAAG
TCAACGTTTTGCTGTTCGGGTTATAATTGTTCTCCAACATGGAAATGGTGTGTCTACGCT
CGTCCTGGACGCCGTTGAAGACCAATATTTTATTATCTGTATCAAAAAAAAAAAAAAAAA
AAAAAAAAA |
Full BLAST
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>as:U1-theraphotoxin-Cg1a_3|gb:EU233835 cDNA sequence of a toxin from the venom gland of the spider Chilobrachys guangxiensis
GAACAGCGACTACACTTAGTATCCCCTGAAGATTCTAGCTATCCGTACGGCGAGTAATCA
TGAAGACGTCCGCTTTATTCGTCATTTTTGGATTAGTCCTGCTTTTCTGCAATTCATTTG
CAGCTGAACTGAAAACGACCGGAAGAGGTTGTGGAGGACTTATGGCTGGATGTGATGGAA
AGTCAACGTTTTGCTGTTCGGGTTATAATCGGCCGGGGGTAACAGCGACTACACTTAATA
TCCCCTGAAGATTCTAGCTATCCGTACGGCGAGTAATCATGAAGACGTCCGCTTTATTCG
TCATTTTTGGATTAGTCCTGCTTTTCTGCAATTCATTTGCAGCTGAACTGGAAATGACCG
GAAGAGGTTGTGGAGGACTCATGGCTGGATGTGATGGAAAGTCAACGTTTTGCTGTTCGG
GTTATAATTGTTCTCCAACATGGAAATGGTGTGTCTACGCTCGTCCTGGACGCCGTTGAA
GACCAATATTTTATTATCTGTATCAACAAGAAAATTTGAGCACTTCCGTTGTGACATGAA
ATTTAAATGAAACTTGAATAAAAGGAAAATCAGCATGCACAATAAGAAAAAAAAAAAAAA
AAAAAAAAA |
Full BLAST
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| Synonym |
Type |
| U1-theraphotoxin-Cg1a |
Recommended full name |
| U1-TRTX-Cg1a |
Recommended abbreviation |
| JzTx-7.2 |
Recommended abbreviation |
| Jingzhaotoxin-7 |
Synonym |
| Jingzhaotoxin-VII |
Synonym |
| U1-theraphotoxin-Cj1a |
Synonym |
| Jingzhaotoxin-7.2 |
Synonym |
| U1-TRTX-Cj1a |
Synonym (abbreviation) |
| JzTx-7 |
Synonym (abbreviation) |
| JzTx-VII |
Synonym (abbreviation) |
| JzTx-7.2 |
Synonym (abbreviation) |
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